Sea como fuere, el tratamiento prolongado con nitratos se suele acompañar de En aquellos pacientes que presentan angina de Prinzmetal sobre un fondo de . We present 2 cases of severe vasospastic angina resistant to intensive medical vagal tone associated with thyrotoxicosis triggers prinzmetal variant angina and Un tratamiento a tener en cuenta en la tirotoxicosis inducida por amiodarona. S: Coronary arterial spasm and Prinzmetal’s variant form of angina induced by hyperventilation and Tris-buffer infusion. Circulation 56, A lead ECG was obtained. From the Cattedra di Fisiopatologia Cardiorespiratoria dell.

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Subscriber If you already have your login data, please click here. For the management of this entity, it is essential to control the thyroid activity, which can be curative in itself, obviating the need for subsequent antianginal therapy, 5 especially if there is no accompanying heart disease. Forty-eight hours later, a level of free thyroxine of 4. Previous Article Vol Images subject to Copyright. Iberoamerican Cardiovascular Journals Editors’ Network. Are you a health professional able to prescribe or dispense drugs?

We present 2 cases of severe vasospastic angina resistant to intensive medical treatment. A year-old man was brought fisiopatilogia our hospital with acute myocardial infarction and precordial ST elevation.

The free thyroxine level was 6. This time, coronary angiography revealed diffuse spasm in mid-distal ADA Figure 2which was controlled with intracoronary nitroglycerin.

Thyrotoxicosis-Induced Vasospastic Angina | Revista Española de Cardiología (English Edition)

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Previous article Next article. Continuing navigation will be considered as acceptance of this use. One year after the initiation of this medication, he was admitted to the hospital with unstable angina, with mild electrical and enzymatic changes.

Calls from Spain 88 87 40 9 to 18 hours. The main characteristic of the initial clinical course was the difficult management, with frequent anginal episodes, despite the use of high-dose calcium antagonists and nitrates. Finally, prinzmetwl patient underwent total thyroidectomy, without subsequent recurrence of anginal episodes, even after the calcium antagonists were discontinued 2 months after the surgical procedure.

Thyrotoxicosis-Induced Vasospastic Angina

After having experienced several documented episodes of atrial fibrillation and nonsustained ventricular tachycardia, the patient began to receive treatment with amiodarone, in addition to the carvedilol that he was already taking.

To improve our services and products, we use “cookies” own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer fiwiopatologia. He underwent primary angioplasty with conventional stent implantation in mid ADA.

Once the diagnosis of hyperthyroidism is established, medical treatment usually suffices, although, in severe cases, most of which are induced by amiodarone, thyroidectomy may be necessary. SRJ is a prestige metric based on the idea that not all citations are the same.

These manuscripts fisiopatoligia updated topics with a major clinical or conceptual relevance in modern medicine. Print Send to a friend Export reference Mendeley Statistics.

Hospital General Universitario de Alicante. With a diagnosis of Graves’ disease, the hyperthyroidism was controlled with carbimazole, and the patient has remained asymptomatic after 8 months of follow-up with no need for calcium antagonists, which were discontinued 45 days after he was discharged. Subscribe to fisiopatilogia Newsletter. A repeated coronary angiography revealed visiopatologia diffuse, severe spontaneous spasm of anterior descending artery ADA Figure 1which reproduced the admission clinical onset.


The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two receding years.

This item nagina received. The patient was a year-old man with dilated cardiomyopathy and angiographically normal coronary arteries in 2 prior catheterizations. The journal adheres to the standards of academic research publications in all aspects including peer-review and ethical principles. The authors wish to thank the reviewers for their comments and the suggested modifications, which contributed considerably to improving the manuscript.

Two weeks later, he was readmitted with the same clinical signs and symptoms and the same electrical changes, accompanied by anxiety and resting tremor. Thus, we highlight the importance of determining thyroid hormone concentrations in cases of vasospastic angina, especially when drug resistance is observed, 4 and even if the signs of hyperthyroidism are mild, 2 a circumstance to which previous treatment with beta-blockers can contribute.

CiteScore measures average citations received per document published.

A second catheterization ruled out complications associated with the previously implanted fisiopatologixas well a development of new lesions, and the patient was discharged on calcium antagonists and nitrates.